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Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM2V3)

ArtNr ITG-MM2V3-100UG
Hersteller KactusBio
Menge 100 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Mouse (Murine, Mus musculus)
Host HEK293
Konjugat/Tag C-hFc
Purity > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Formula Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Sequence Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer
Shipping Temperature
Shipped at ambient temperature.
Storage Conditions
-20 to -80°C for 12 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Bis-Tris PAGE result.
Description
Recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
Background
ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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