« Zurück
Startseite /
Human LAG3 / CD223 Protein, Fc Tag (MALS verified)

Human LAG3 / CD223 Protein, Fc Tag (MALS verified)

ArtNr	LA3-H5255-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 200 ug x 5
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, Fc
Purity	95%
Citations	(1) Triebel F., et al., 1990, J. Exp. Med. 171:1393-1405. (2) Baixeras E., et al., 1992, J. Exp. Med. 176:327-337.
NCBI	NP_002277.4
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LAG3,CD223,FDC
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	72.8 kDa
Manufacturer - Format	Powder
Description	Human LAG-3, Fc Tag (LA3-H5255) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).
Background	Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Molecule	LAG-3
Exp Region	Leu 23 - Leu 450
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH 7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

LA3-H5255-100ug-datasheet.pdf

LA3-H5255-100ug-safety-datasheet.pdf