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Human LBP / Lipopolysaccharide-binding (I465F) Protein, His Tag

Human LBP / Lipopolysaccharide-binding (I465F) Protein, His Tag

ArtNr	LBP-H52H5-1mg
Hersteller	ACROBiosystems
Menge	250 ug x 4
Quantity options	100 ug 250 ug x 4
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	95%
Citations	(1) Schumann R.R., et al., 1990, Science 249:1429-1431. (2) Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430. (3) Eckert J.K., et al., 2013, Immunity 39:647-660.
NCBI	NP_004130.2 (I465F)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Lipopolysaccharide-binding protein,LBP
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	52.8 kDa
Manufacturer - Format	Powder
Description	Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Background	Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Molecule	Lipopolysaccharide-binding protein / LBP
Exp Region	Ala 26 - Val 481
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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LBP-H52H5-1mg-datasheet.pdf

LBP-H52H5-1mg-safety-datasheet.pdf