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PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein (MHC-HM407TP)

ArtNr MHC-HM407TP-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS, Avi
Formula Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Dry ice Yes
Sequence Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FMNKFIYEI peptide
NCBI FMNKFIYEI
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Alpha-fetoprotein,Alpha-1-fetoprotein,Alpha-feto,AFP,HPAFP,AFPD,FETA,MHC
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
HLA-A*02:01&B2M&AFP (FMNKFIYEI)
Manufacturer - Conjugate / Tag
C-His-Avi
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 6 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Description
Recombinant PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FMNKFIYEI peptide.
Background
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
lieferbar

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