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PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416TP)

PE-Labeled Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416TP)

ArtNr	MHC-HM416TP-100UG
Hersteller	KactusBio
Menge	100 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Myelofibrosis Mesothelioma Astrocytoma Blastom
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS, Avi
Formula	Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Dry ice	Yes
Sequence	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and HMTEVVRRC peptide
NCBI	HMTEVVRRC
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MHC,HLA-A,P53,TP53,Antigen NY-CO-13,BCC7,FLJ92943,LFS1,TRP53
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	P53 (HLA-A*02:01)
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 6 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles and protect from light.
Description	Recombinant PE-Labeled Human HLA-A02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A02:01&B2M&P53 WT (HMTEVVRRC) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and HMTEVVRRC peptide.
Background	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

MHC-HM416TP-100UG-datasheet.pdf

MHC-HM416TP-100UG-safety-datasheet.pdf