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PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein (MHC-HM421TP)

PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein (MHC-HM421TP)

ArtNr	MHC-HM421TP-500UG
Hersteller	KactusBio
Menge	500 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Adenocarcinoma Cytoskeleton Myelofibrosis Mesothelioma Astrocytoma By Organ Lung Cancer Colorectal Cancer Heart & Blood Cancer small GTPases Ras Subfamily
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS, Avi
Formula	Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Dry ice	Yes
Sequence	Gly25-Thr305 (HLA-A*11:01), Ile21-Met119(B2M) and VVVGAVGVGK peptide
NCBI	VVVGAVGVGK
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MHC,KRAS,K-Ras 2,KRAS2,C-K-RAS,CFC2,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KRAS1,KRAS2,NS,NS3,RASK2,GTPase Kras,KI-RAS,RALD
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK)
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Description	Recombinant PE-Labeled Human HLA-A11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-labeled Human HLA-A11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin.; It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGAVGVGK peptide.
Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

MHC-HM421TP-500UG-datasheet.pdf

MHC-HM421TP-500UG-safety-datasheet.pdf