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Human NKG2C&CD94 Protein, Fc Tag Europäischer Partner

ArtNr NC4-H5258-1mg
Hersteller ACROBiosystems
Menge 500 ug x 2
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 95%
Citations (1) Petrie EJ. J Exp Med. 2008. 205(3):725-35. (2) Kaiser BK. Proc Natl Acad Sci U S A. 2008. 105(18):6696-701. (3) Sun C, et al. Oncoimmunology. 2016. 6(1):e1264562.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NKG2C & CD94
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
57.1 kDa
Manufacturer - Format
Powder
Description
Human NKG2C&CD94, Fc Tag (NC4-H5258) is expressed from human 293 cells (HEK293). It contains AA Ile 94 - Leu 231 (NKG2C) & Asp 57 - Ile 179 (CD94) (Accession # P26717-1 (NKG2C) & Q13241-1 (CD94) (F102S, mutation caused by sequence update)).
Background
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
Molecule
NKG2C & CD94
Exp Region
Ile 94 - Leu 231 (NKG2C) & Asp 57 - Ile 179 (CD94)
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.1 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug x 2
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 19.02.2026 

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