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Recombinant human Aldo-keto Reductase 1C3/AKR1C3 protein

ArtNr NKM-ATGP0270-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD
Citations Davies N., et al. (2009) Cancer Res. 69(11):4769-75
Kabututu Z., et al. (2009) J Biochem. 145(2):161-8
NCBI NP_003730.4
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Aldo-keto reductase family 1 member C3,DD3,DDX,HA1753,HAKRB,HAKRe,hluPGFS,HSD17B5,Aldo-keto reductase family 1,member C3 17 beta HSD 5(HSD17B5),AKR1 C3,Chlordecone reductase,17 beta hydroxysteroid dehydrogenase type 5,DDH1,PGFS,Prostaglandin F synthase
Similar products AKR1C3, DDX, PGFS, DD3, Chlordecone reductase, Aldo-keto reductase family 1 member C3, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS, DDH1, Prostaglandin F synthase, member C3, 17 beta hydroxysteroid dehydrogenase type 5, AKR1 C3, Aldo keto reductase family 1 member C3, Aldo-keto reductase family 1, Aldo-keto Reductase1C3, member C3 17 beta HSD 5, ATGP0270-10ug, ATGP0270-20ug, ATGP0270-50ug, ATGP0270-100ug, ATGP0270-250ug, ATGP0270-500ug, ATGP0270-1mg, ATGP0270-10, ATGP0270-20, ATGP0270-50, ATGP0270-100, ATGP0270-250, ATGP0270-500, ATGP0270-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
39 kDa (343aa) confirmed by MALDI-TOF
Description
AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-323aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 1, 000pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0pmole 1-Acenaphthenol in the presence of NADP per minute at pH 8.8 at 25C.
Species of Protein
Human
Manufacturer - Search Terms
Aldo-keto Reductase1C3, AKR1C3, Aldo-keto reductase family 1 member C3, Aldo-keto reductase family 1, member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, KIAA0119, Aldo-keto reductase family 1, member C3 17 beta HSD 5, AKR1 C3, Chlordecone reductase, 17 beta hydroxysteroid dehydrogenase type 5, Aldo keto reductase family 1 member C3, DDH1, HAKRe, HSD17B5, PGFS, Prostaglandin F synthase, ATGP0270-10ug, ATGP0270-20ug, ATGP0270-50ug, ATGP0270-100ug, ATGP0270-250ug, ATGP0270-500ug, ATGP0270-1mg, ATGP0270-10, ATGP0270-20, ATGP0270-50, ATGP0270-100, ATGP0270-250, ATGP0270-500, ATGP0270-1
Manufacturer - Alternative Names
Aldo-keto reductase family 1 member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Aldo-keto reductase family 1, member C3 17 beta HSD 5(HSD17B5), AKR1 C3, Chlordecone reductase, 17 beta hydroxysteroid dehydrogenase type 5, DDH1, PGFS, Prostaglandin F synthase

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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