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Recombinant human VEGF 121/VEGFA protein

ArtNr NKM-ATGP0282-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR
Citations Yasuji ueda., et al. (2004) Cancer Chemother Pharmacol. 54(1):16-24.
Neufeld G., et al. (1999) FASEB J. 13(1):9-22.
NCBI NP_001020541.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Vascular endothelial growth factor A isoform f,Vascular permeability factor,VPF,VEGF
Similar products VEGF121, ATGP0282-10ug, ATGP0282-20ug, ATGP0282-50ug, ATGP0282-100ug, ATGP0282-250ug, ATGP0282-500ug, ATGP0282-1mg, ATGP0282-10, ATGP0282-20, ATGP0282-50, ATGP0282-100, ATGP0282-250, ATGP0282-500, ATGP0282-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
14.2 kDa (122aa) confirmed by MALDI-TOF
Description
Vascular endothelial growth factor (VEGF) is homodimeric, heparin-binding glycoprotein involved in both angiogenesis and vasculogenesis. VEGF is expressed as multiple alternately spliced isoforms of VEGF121, 165, 189 and 206. VEGF binds to the receptor tyrosine kinases VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1) to activate signal transduction and regulate both physiological and pathological angiogenesis. Recombinant VEGF121 protein was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10 % glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
207-327aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 range ≤4ng/ml.
Species of Protein
Human
Manufacturer - Search Terms
VEGF121, ATGP0282-10ug, ATGP0282-20ug, ATGP0282-50ug, ATGP0282-100ug, ATGP0282-250ug, ATGP0282-500ug, ATGP0282-1mg, ATGP0282-10, ATGP0282-20, ATGP0282-50, ATGP0282-100, ATGP0282-250, ATGP0282-500, ATGP0282-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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