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Recombinant human GRB2 protein

ArtNr NKM-ATGP0286-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG DFIHVMDNSD PNWWKGACHG QTGMFPRNYV
Citations Rudd CE., et al. (2009) Immunol Rev. 229(1):12-26.
Weisswange I., et al. (2009) Nature. 458(7234):87-91.
NCBI NP_002077.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Growth factor receptor-bound protein 2 isoform 1,Growth factor receptor-bound protein 2 isoform 1,ASH,EGFRBP-GRB2,GRB3-3,Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology,Adapter protein GRB2,Ash protein,EGFRBP GRB2,Epidermal growth factor receptor binding protein,Epidermal growth factor receptor binding protein GRB2,GRB 2,GRB2 adapter protein,Grb3 3,Growth factor receptor bound protein 2,Growth factor receptor bound protein 3,HT027,MST084,MSTP084,OTTHuMP00000166096,OTTHuMP00000166097,OTTHuMP00000166098,Protein ASH,SEM5,SH2/SH3 adapter GRB2.
Similar products GRB2, ASH, EGFRBP-GRB2, MST084, MSTP084, HT027, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, SEM5, Growth factor receptor-bound protein 2 isoform 1, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SH2/SH3 adapter GRB2., ATGP0286-10ug, ATGP0286-20ug, ATGP0286-50ug, ATGP0286-100ug, ATGP0286-250ug, ATGP0286-500ug, ATGP0286-1mg, ATGP0286-10, ATGP0286-20, ATGP0286-50, ATGP0286-100, ATGP0286-250, ATGP0286-500, ATGP0286-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
27 kDa (237aa) confirmed by MALDI-TOF
Description
Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. GRB2 is widely expressed and also binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Inhibition of Grb2 function impairs developmental processes in various organisms and blocks transformation and proliferation of various cell types. Recombinant human GRB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-217aa
Species of Protein
Human
Manufacturer - Search Terms
GRB2, Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2., ATGP0286-10ug, ATGP0286-20ug, ATGP0286-50ug, ATGP0286-100ug, ATGP0286-250ug, ATGP0286-500ug, ATGP0286-1mg, ATGP0286-10, ATGP0286-20, ATGP0286-50, ATGP0286-100, ATGP0286-250, ATGP0286-500, ATGP0286-1
Manufacturer - Alternative Names
Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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