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Recombinant human FKBP12/FKBP1A protein

ArtNr NKM-ATGP0290-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE
Citations Jayaraman T., et al. (1992). J Biol Chem. 267(14):9474-7
Siekierka JJ., et al. (1990). J Biol Chem. 265(34):21011-5
NCBI NP_463460.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FKBP prolyl isomerase 1A,FKBP1,FK506 binding protein 1a 12kDa,PPIase FKBP1A,Rotamase,12 kDa FKBP,FK506 binding protein 1,FK506 binding protein 1A 12kDa,Immunophilin FKBP12,FK506 binding protein T cell 12 kD,FK506 binding protein 12,FKBP 12,FKBP12 Exip3,FKBP12C,Peptidyl-prolyl cis-trans isomerase,PKCI2,PPIase,Protein kinase C inhibitor 2,calstabin 1,Rotamase
Similar products PPIase, Rotamase, FKBP1, FKBP12, FKBP12C, PKC12, PKCI2, Peptidyl-prolyl cis-trans isomerase, Immunophilin FKBP12, FK506 binding protein 1, FK506 binding protein 12, FK506 binding protein 1A 12kDa, FK506 binding protein T cell 12 kD, FK506-binding protein 1A, FKBP 12, FKBP 1A, FKBP12 Exip3, PPIase FKBP1A, FKBP1a, FK506 binding protein 1a 12kDa, FK506 binding protein 1a, 12kDa 12 kDa FKBP, Protein kinase C inhibitor 2., ATGP0290-10ug, ATGP0290-20ug, ATGP0290-50ug, ATGP0290-100ug, ATGP0290-250ug, ATGP0290-500ug, ATGP0290-1mg, ATGP0290-10, ATGP0290-20, ATGP0290-50, ATGP0290-100, ATGP0290-250, ATGP0290-500, ATGP0290-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
14.1 kDa (128aa) confirmed by MALDI-TOF
Description
FK506 binding protein 1a, also known as FKBP12, belongs to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1, 4, 5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. Recombinant human FKBP12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Heat Shock Proteins
Domain
1-108aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 800nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
Species of Protein
Human
Manufacturer - Search Terms
FKBP1a , FKBP12, FK506 binding protein 1a 12kDa, PPIase FKBP1A, Rotamase, FKBP1, PKC12, FK506 binding protein 1a, 12kDa 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 1A 12kDa, Immunophilin FKBP12, FK506 binding protein T cell 12 kD, FK506-binding protein 1A, FK506 binding protein 12, FKBP 12, FKBP 1A, FKBP12, FKBP12 Exip3, FKBP12C, Peptidyl-prolyl cis-trans isomerase, PKCI2, PPIase, Protein kinase C inhibitor 2., ATGP0290-10ug, ATGP0290-20ug, ATGP0290-50ug, ATGP0290-100ug, ATGP0290-250ug, ATGP0290-500ug, ATGP0290-1mg, ATGP0290-10, ATGP0290-20, ATGP0290-50, ATGP0290-100, ATGP0290-250, ATGP0290-500, ATGP0290-1
Manufacturer - Alternative Names
FKBP prolyl isomerase 1A, FKBP1, FK506 binding protein 1a 12kDa, PPIase FKBP1A, Rotamase, 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 1A 12kDa, Immunophilin FKBP12, FK506 binding protein T cell 12 kD, FK506 binding protein 12, FKBP 12, FKBP12 Exip3, FKBP12C, Peptidyl-prolyl cis-trans isomerase, PKCI2, PPIase, Protein kinase C inhibitor 2, calstabin 1, Rotamase

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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