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Recombinant human FKBP52/FKBP4 protein

ArtNr NKM-ATGP0303-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MTAEEMKATE SGAQSAPLPM EGVDISPKQD EGVLKVIKRE GTGTEMPMIG DRVFVHYTGW LLDGTKFDSS LDRKDKFSFD LGKGEVIKAW DIAIATMKVG EVCHITCKPE YAYGSAGSPP KIPPNATLVF EVELFEFKGE DLTEEEDGGI IRRIQTRGEG YAKPNEGAIV EVALEGYYKD KLFDQRELRF EIGEGENLDL PYGLERAIQR
Citations Ostrow KL., et al. (2009) Clin Cancer Res. 15(4):1184-91
Ma D., et al. (2008) J Biol Chem. 283(38):25963-70
NCBI NP_002005.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FK506 binding protein 4,FK506 binding protein 4 52 kDa FK506 binding protein,FKBP 4,FKBP 52,FKBP 59,HBI,Hsp 56,HSP binding immunophilin,p52,p59 protein,Peptidylprolyl cis trans isomerase,PPIase,Rotamase,T cell FK506 binding protein 59kD
Similar products FKBP4, PPIase, Rotamase, FKBP52, FKBP59, HBI, Hsp56, p52, HSP binding immunophilin, p59 protein, Peptidyl prolyl cis trans isomerase, Peptidylprolyl cis trans isomerase, Hsp 56, FK506 binding protein 4, FKBP 4, FKBP 52, FKBP 59, FKBP52 protein, T cell FK506 binding protein 59kD., FK506 binding protein 4 52 kDa FK506 binding protein, ATGP0303-10ug, ATGP0303-20ug, ATGP0303-50ug, ATGP0303-100ug, ATGP0303-250ug, ATGP0303-500ug, ATGP0303-1mg, ATGP0303-10, ATGP0303-20, ATGP0303-50, ATGP0303-100, ATGP0303-250, ATGP0303-500, ATGP0303-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
53.9 kDa (479aa) confirmed by MALDI-TOF
Description
FKBP4, also known as FKBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. Recombinant human FKBP4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Heat Shock Proteins
Domain
1-459aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 700nmol/min/mg, and is defined as the amount of cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
Species of Protein
Human
Manufacturer - Search Terms
FKBP52, FKBP4, FK506 binding protein 4, FKBP52, FKBP59, HBI, Hsp56, p52, PPIase, FK506 binding protein 4 52 kDa FK506 binding protein, FKBP 4, FKBP 52, FKBP 59, FKBP4, FKBP52 protein, FKBP59, Hsp 56, HSP binding immunophilin, p59 protein, PPIase, Rotamase, Peptidyl prolyl cis trans isomerase, Peptidylprolyl cis trans isomerase, T cell FK506 binding protein 59kD., ATGP0303-10ug, ATGP0303-20ug, ATGP0303-50ug, ATGP0303-100ug, ATGP0303-250ug, ATGP0303-500ug, ATGP0303-1mg, ATGP0303-10, ATGP0303-20, ATGP0303-50, ATGP0303-100, ATGP0303-250, ATGP0303-500, ATGP0303-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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