Vergleich

Recombinant human Smad2 protein

ArtNr NKM-ATGP0307-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG LYSFSEQTRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELKAIENCE YAFNLKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEILTEL PPLDDYTHSI PENTNFPAGI
Citations Bonni., et al. (2001) Nat. Cell Biol. 3(6): 587-95.
Wotton, et al. (1999) Cell. 97(1): 29-39.

Jung SH, et al. Integrative proteomic profiling of protein activity and interactions using protein arrays. (Mol Cell Proteomics. 2012){https://pubmed.ncbi.nlm.nih.gov/22843993/}
Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27040940/}
Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017){https://pubmed.ncbi.nlm.nih.gov/28536714/}
NCBI NP_005892.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Sma- and Mad-related protein 2 isoform 1,Sma- and Mad-related protein 2 isoform 1,hMAD-2,hSMAD2,JV18,JV18-1,MADH2,MADR2,Sma- and Mad-related protein 2 isoform 1 JV181,MAD,MAD Related Protein 2,SMAD2.
Similar products Smad2, MAD, JV18-1, MADH2, hSMAD2, hMAD-2, JV18, MADR2, MAD Related Protein 2, Sma- and Mad-related protein 2 isoform 1, Sma- and Mad-related protein 2 isoform 1 JV181, SMAD2., ATGP0307-10ug, ATGP0307-20ug, ATGP0307-50ug, ATGP0307-100ug, ATGP0307-250ug, ATGP0307-500ug, ATGP0307-1mg, ATGP0307-10, ATGP0307-20, ATGP0307-50, ATGP0307-100, ATGP0307-250, ATGP0307-500, ATGP0307-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.4 kDa (487aa)
Description
SMAD2 (Mothers against decapentaplegic homolog 2) belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Phosphorylated Smad2 is then able to form a complex with Smad4 or SARA. These complexes accumulate in the cell nucleus, where they are directly participating in the regulation of gene expression. Recombinant SMAD2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-467aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Smad2, Sma- and Mad-related protein 2 isoform 1, Sma- and Mad-related protein 2 isoform 1, hMAD-2, hSMAD2, JV18, JV18-1, MADH2, MADR2, Sma- and Mad-related protein 2 isoform 1 JV181, MAD, MAD Related Protein 2, SMAD2., ATGP0307-10ug, ATGP0307-20ug, ATGP0307-50ug, ATGP0307-100ug, ATGP0307-250ug, ATGP0307-500ug, ATGP0307-1mg, ATGP0307-10, ATGP0307-20, ATGP0307-50, ATGP0307-100, ATGP0307-250, ATGP0307-500, ATGP0307-1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen