Recombinant human Visinin-like protein-1/VILIP protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Neuroscience

< 1 EU per 1ug of protein (determined by LAL method)

Visinin-like protein1, VILIP, VILIP-1, VLP-1, HLP3, VSNL1, Hippocalcin like protein 3, HLP 3, HPCAL 3, HPCAL3, HuVISL1, Neurocalcin alpha, NVL 1, NVL1, VILIP, Visinin.Visinin like 1, Visinin like protein 1.VISL 1., ATGP0384-10ug, ATGP0384-20ug, ATGP0384-50ug, ATGP0384-100ug, ATGP0384-250ug, ATGP0384-500ug, ATGP0384-1mg, ATGP0384-10, ATGP0384-20, ATGP0384-50, ATGP0384-100, ATGP0384-250, ATGP0384-500, ATGP0384-1