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Recombinant human Smad3 protein

ArtNr NKM-ATGP0421-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN
Citations Zhang Y., et al. (1996) Nature. 383(6596):168-72.
Wang H., et al. (2005) J Biol Chem. 280(7):5154-62.
NCBI NP_005893
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mothers against decapentaplegic homolog 3,HSPC193,HsT17436,JV15-2,MADH3,Mothers against decapentaplegic homolog 3 DKFZP586N0721,DKFZp686J10186,hMAD 3,hSMAD3,MAD (mothers against decapentaplegic Drosophila) homolog 3,HST17436,JV15 2,JV152,MAD3,MADH 3,MGC60396,Mothers against DPP homolog 3,SMA and MAD related protein 3,SMAD,SMAD 3,SMAD3,
Similar products Smad3, ATGP0421-10ug, ATGP0421-20ug, ATGP0421-50ug, ATGP0421-100ug, ATGP0421-250ug, ATGP0421-500ug, ATGP0421-1mg, ATGP0421-10, ATGP0421-20, ATGP0421-50, ATGP0421-100, ATGP0421-250, ATGP0421-500, ATGP0421-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
50.2 kDa (445aa) confirmed by MALDI-TOF
Description
SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl and 1mM DTT
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-425aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Smad3, ATGP0421-10ug, ATGP0421-20ug, ATGP0421-50ug, ATGP0421-100ug, ATGP0421-250ug, ATGP0421-500ug, ATGP0421-1mg, ATGP0421-10, ATGP0421-20, ATGP0421-50, ATGP0421-100, ATGP0421-250, ATGP0421-500, ATGP0421-1
Manufacturer - Alternative Names
Mothers against decapentaplegic homolog 3, HSPC193, HsT17436, JV15-2, MADH3, Mothers against decapentaplegic homolog 3 DKFZP586N0721, DKFZp686J10186, hMAD 3, hSMAD3, MAD (mothers against decapentaplegic Drosophila) homolog 3, HST17436, JV15 2, JV152, MAD3, MADH 3, MGC60396, Mothers against DPP homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD3

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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