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Recombinant human BAG3 protein

ArtNr NKM-ATGP0440-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSAATHSPMM QVASGNGDRD PLPPGWEIKI DPQTGWPFFV DHNSRTTTWN DPRVPSEGPK ETPSSANGPS REGSRLPPAR EGHPVYPQLR PGYIPIPVLH EGAENRQVHP FHVYPQPGMQ RFRTEAAAAA PQRSQSPLRG MPETTQPDKQ CGQVAAAAAA QPPASHGPER SQSPAASDCS SSSSSASLPS SGRSSLGSHQ LPRGYISIPV
Citations Virador VM., et al. (2009) PLos One. 4(4):e5136.
Kyratsous CA., et al. (2008) Proc Natl Acad Sci u S A. 105(52):20912-7.
NCBI NP_004272.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BAG family molecular chaperone regulator 3,BIS,CAIR-1,BAG family molecular chaperone regulator 3 BAG 3,Bcl 2 binding protein,BCL2 associated athanogene 3,BCL2 binding athanogene 3,Docking protein CAIR 1.
Similar products BAG3, BIS, CAIR-1, BAG family molecular chaperone regulator 3, BCL2 associated athanogene 3, BCL2 binding athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3 BAG 3, Docking protein CAIR 1., ATGP0440-10ug, ATGP0440-20ug, ATGP0440-50ug, ATGP0440-100ug, ATGP0440-250ug, ATGP0440-500ug, ATGP0440-1mg, ATGP0440-10, ATGP0440-20, ATGP0440-50, ATGP0440-100, ATGP0440-250, ATGP0440-500, ATGP0440-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
63.7 kDa (595aa)
Description
BAG3 was reported initially as a protein-refolding cochaperone of the bcl2 binding protein BAG family and as upregulated in response to persistent stress of cellular calcium balance dysregulation. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. Also, it has been shown to diminish stress-induced apoptosis. Recombinant human BAG3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM EDTA, 0.1mM PMSF, 10% glycerol
Antigen Species
Human
Gene Category
Heat Shock Proteins
Domain
1-575aa
Species of Protein
Human
Manufacturer - Search Terms
BAG3, BAG family molecular chaperone regulator 3, BIS, CAIR-1, BAG family molecular chaperone regulator 3 BAG 3, Bcl 2 binding protein, BCL2 associated athanogene 3, BCL2 binding athanogene 3, Docking protein CAIR 1., ATGP0440-10ug, ATGP0440-20ug, ATGP0440-50ug, ATGP0440-100ug, ATGP0440-250ug, ATGP0440-500ug, ATGP0440-1mg, ATGP0440-10, ATGP0440-20, ATGP0440-50, ATGP0440-100, ATGP0440-250, ATGP0440-500, ATGP0440-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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