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Recombinant human Aldolase A/ALDOA protein

ArtNr NKM-ATGP0477-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MPYQYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL
Citations Pfleiderer G., et al. (1975) Beitr Pathol. 156(3):266-79.
Kishi H., et al. (1987) Proc Natl Acad uSA. 84(23):8623-7.
Jung SH, et al. Integrative Proteomic Profiling of Protein Activity and Interactions Using Protein Arrays. (Mol Cell Proteomics. 2012){https://www.ncbi.nlm.nih.gov/pubmed/22843993}
Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27040940/}
Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017){https://pubmed.ncbi.nlm.nih.gov/28536714/}
NCBI NP_908930
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Fructose-bisphosphate aldolase A,Lung cancer antigen NY-LU-1,Muscle-type aldolase,ALDA
Similar products ALDOA, Aldolase A, ALDA, GSD12, MGC10942, MGC17716, MGC17767, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase A, Fructose bisphosphate aldolase, Muscle type aldolase, Fructose bisphosphate aldolase A Aldolase A, Lung cancer antigen NY Lu 1, ATGP0477-10ug, ATGP0477-20ug, ATGP0477-50ug, ATGP0477-100ug, ATGP0477-250ug, ATGP0477-500ug, ATGP0477-1mg, ATGP0477-10, ATGP0477-20, ATGP0477-50, ATGP0477-100, ATGP0477-250, ATGP0477-500, ATGP0477-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
41.5 kDa (384aa) confirmed by MALDI-TOF
Description
Fructose bisphosphate aldolase A, also known as Aldolase A is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. It is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Deficiency has been associated with myopathy and hemolytic anemia. Recombinant human Aldolase A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 10% glycerol
Antigen Species
Human
Gene Category
Metabolism
Domain
1-364aa
Bioactivity Comment Only
Specific activity is > 10unit/mg, one unit will convert 1.0 umol of fructose 1, 6-diphosphate to dihydroxyacetone phosphate and glyceraldehydes 3-phosphate per minute at pH 7.5 at 37C.
Species of Protein
Human
Manufacturer - Search Terms
Aldolase A, Fructose bisphosphate aldolase A, ALDOA, ALDA, GSD12, Fructose bisphosphate aldolase A Aldolase A, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase, Lung cancer antigen NY Lu 1, MGC10942, MGC17716, MGC17767, Muscle type aldolase, ATGP0477-10ug, ATGP0477-20ug, ATGP0477-50ug, ATGP0477-100ug, ATGP0477-250ug, ATGP0477-500ug, ATGP0477-1mg, ATGP0477-10, ATGP0477-20, ATGP0477-50, ATGP0477-100, ATGP0477-250, ATGP0477-500, ATGP0477-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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