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Recombinant human Profilin 2/PFN2 protein

ArtNr NKM-ATGP0535-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF
Citations Gieslmann R., et al. (1995) Eur J Bilchem. 229(3):621-8.
Reinhard M., et al. (1995) EMBO J. 14(8):1583-9.
NCBI AAH18049
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Profilin 2,PFL,Profilin 2 D3S1319E,PFN 2,PFN2,Profilin II,ProfilinII,Profilin2
Similar products PFN2, Profilin II, PFL, Profilin 2, PFN 2, Profilin2, ProfilinII, Profilin 2 D3S1319E, ATGP0535-10ug, ATGP0535-20ug, ATGP0535-50ug, ATGP0535-100ug, ATGP0535-250ug, ATGP0535-500ug, ATGP0535-1mg, ATGP0535-10, ATGP0535-20, ATGP0535-50, ATGP0535-100, ATGP0535-250, ATGP0535-500, ATGP0535-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17.2 kDa (160aa) confirmed by MALDI-TOF
Description
PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Cytoskeleton
Domain
1-140aa
Species of Protein
Human
Manufacturer - Search Terms
PFN2, Profilin 2, PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2, ATGP0535-10ug, ATGP0535-20ug, ATGP0535-50ug, ATGP0535-100ug, ATGP0535-250ug, ATGP0535-500ug, ATGP0535-1mg, ATGP0535-10, ATGP0535-20, ATGP0535-50, ATGP0535-100, ATGP0535-250, ATGP0535-500, ATGP0535-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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