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Recombinant human RUNX3/CBFA3 protein

ArtNr NKM-ATGP0576-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK
Citations Vogiatzi P. et al. (2006) Cancer Biol Ther. 5(4):371-4.
Li QL,et al. (2002)Cell. 109(1):113-24.
NCBI NP_004341
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Runt-related transcription factor 3,AML2,CBFA3,PEBP2aC,Runt-related transcription factor 3 Acute myeloid leukemia 2 protein,Acute myeloid leukemia gene 2,AML 2,CBF alpha 3,CBFA 3,Core binding factor alpha 3 subunit,core binding factor,Core binding factor runt domain alpha subunit 3,Core binding factor subunit alpha 3.M574,core-binding factor,FLJ34510,MGC16070,Oncogene AML 2,PEA2 alpha C,PEBP2 alpha C,Pebp2a3,Polyomavirus enhancer binding protein 2 alpha C subunit,runt domain alpha subunit 3,runt related transcription factor 3,RuNX 3,SL3 3 enhancer factor 1 alpha C subunit,SL3/AKV core binding factor alpha C subunit,Transcription factor AML2.
Similar products RUNX3, AML2, CBFA3, Runt-related transcription factor 3, core-binding factor, FLJ34510, MGC16070, PEBP2aC, PEA2 alpha C, PEBP2 alpha C, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Oncogene AML 2, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Core binding factor subunit alpha 3.M574, RuNX 3, Transcription factor AML2., ATGP0576-10ug, ATGP0576-20ug, ATGP0576-50ug, ATGP0576-100ug, ATGP0576-250ug, ATGP0576-500ug, ATGP0576-1mg, ATGP0576-10, ATGP0576-20, ATGP0576-50, ATGP0576-100, ATGP0576-250, ATGP0576-500, ATGP0576-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17.1 kDa (155aa) confirmed by MALDI-TOF
Description
RuNX3, also known as runt-related transcription factor 3, belongs to the RuNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RuNX3, fused to His-tag at N-terminus, protein was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
53-186aa
Species of Protein
Human
Manufacturer - Search Terms
RUNX3, CBFA3, Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2., ATGP0576-10ug, ATGP0576-20ug, ATGP0576-50ug, ATGP0576-100ug, ATGP0576-250ug, ATGP0576-500ug, ATGP0576-1mg, ATGP0576-10, ATGP0576-20, ATGP0576-50, ATGP0576-100, ATGP0576-250, ATGP0576-500, ATGP0576-1
Manufacturer - Alternative Names
Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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