Recombinant human NCK1 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

NCK adaptor protein 1, also known as NCK, belongs to the adaptor family of proteins. The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Overexpression of Nck resulted in transformation of NIH 3T3 and 3Y1 rat fibroblast. Recombinant human NCK1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50mM NaCl

Cancer

Human

NCK adaptor protein 1, NCK, NCKalpha, NCK adaptor protein 1 GRB4, melanoma NCK protein, MGC12668, NCK adaptor protein 2, NCK tyrosine kinase, NCKbeta, non catalytic region of tyrosine kinase, noncatalytic region of tyrosine kinase, beta, SH2/SH3 adaptor protein NCK alpha, SH2/SH3 adaptor protein NCK beta.