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Recombinant human Transgelin/TAGLN protein

ArtNr NKM-ATGP0602-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA AEDYGVIKTD MFQTVDLFEG KDMAAVQRTL MALGSLAVTK NDGHYRGDPN WFMKKAQEHK REFTESQLQE GKHVIGLQMG SNRGASQAGM TGYGRPRQII S
Citations Kobayashi R., et al. (1994) Biochem Biophys Res Commun. 198(3):1275-80.
Thweatt R., et al. (1992) Biochem Biophys Res Commun. 187(1):1-7.
NCBI NP_001001522
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias WS3-10,Transgelin,TAGLN1,Smooth muscle protein 22-alpha,SMCC,SM22 alpha,SM22
Similar products TAGLN, SMCC, SM22, TAGLN1, WS3-10, SM22-alpha, Transgelin, SM22 alpha, Smooth muscle protein 22-alpha, WS3 10, Smooth muscle protein 22 alpha, SM 22, TAGLN 1, TAGLN-1, WS310, ATGP0602-10ug, ATGP0602-20ug, ATGP0602-50ug, ATGP0602-100ug, ATGP0602-250ug, ATGP0602-500ug, ATGP0602-1mg, ATGP0602-010, ATGP0602-020, ATGP0602-050, ATGP0602-100, ATGP0602-250, ATGP0602-500, ATGP0602-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.8 kDa (221aa) confirmed by MALDI-TOF
Description
TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Cytoskeleton
Domain
1-201aa
Species of Protein
Human
Manufacturer - Search Terms
SM 22, SM22, SM22 alpha, SM22-alpha, SMCC, Smooth muscle protein 22 alpha, Smooth muscle protein 22-alpha, TAGLN, TAGLN 1, TAGLN1, TAGLN-1, Transgelin, WS3 10, WS310, WS3-10, ATGP0602-10ug, ATGP0602-20ug, ATGP0602-50ug, ATGP0602-100ug, ATGP0602-250ug, ATGP0602-500ug, ATGP0602-1mg, ATGP0602-010, ATGP0602-020, ATGP0602-050, ATGP0602-100, ATGP0602-250, ATGP0602-500, ATGP0602-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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