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Recombinant human K-Ras protein

ArtNr NKM-ATGP0609-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKC
Citations Lee W., et al. (2010) Nature. 465(7297):473-7.
Singh M., et al. (2010) Nat Biotechnol. 28(6):585-93
NCBI AAH13572.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GTPase Kras,KRAS proto-oncogene GTPase,KRAS2,v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog,v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,Kirsten rat sarcoma viral oncogene homolog,KRAS1,K-Ras4B,K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras,RASK2
Similar products RASK2, K-RAS, NS3, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3, GTPase Kras, ATGP0609-10ug, ATGP0609-20ug, ATGP0609-50ug, ATGP0609-100ug, ATGP0609-250ug, ATGP0609-500ug, ATGP0609-1mg, ATGP0609-10, ATGP0609-20, ATGP0609-50, ATGP0609-100, ATGP0609-250, ATGP0609-500, ATGP0609-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
23.2 kDa (205aa) confirmed by MALDI-TOF
Description
KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Cancer
Domain
1-185aa (partial)
Species of Protein
Human
Manufacturer - Search Terms
K-RAS, GTPase Kras, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras, K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3, ATGP0609-10ug, ATGP0609-20ug, ATGP0609-50ug, ATGP0609-100ug, ATGP0609-250ug, ATGP0609-500ug, ATGP0609-1mg, ATGP0609-10, ATGP0609-20, ATGP0609-50, ATGP0609-100, ATGP0609-250, ATGP0609-500, ATGP0609-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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