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Recombinant mouse alpha-Synuclein protein

ArtNr NKM-ATGP0619-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Konjugat/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA
Citations ueda K., et al. (1993) Proc. Natl. Acad. Sci. uSA 90:11282-11286
Kim J., et al. (1997) Molecules and Cells 7:78-83
Jakes R., et al. (1994) FEBS lett. 345:27-32.

Kim S, et al. Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP. (J Neurochem. 2009){https://pubmed.ncbi.nlm.nih.gov/19457162/}
Joo SH, et al. Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells. (Neurosci Lett. 2010){https://pubmed.ncbi.nlm.nih.gov/20026244/}
Lee HJ, et al. Enzyme-linked immunosorbent assays for α-synuclein with species and multimeric state specificities. (J Neurosci Methods. 2011){https://pubmed.ncbi.nlm.nih.gov/21658411/}
Park HJ, et al. Mesenchymal stem cells enhance α-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder. (Acta Neuropathol. 2016){https://pubmed.ncbi.nlm.nih.gov/27497943/}
NCBI NP_033247
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias alpha-Synuclein,Snca,Syn,alpha-Synuclein,NACP,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor
Similar products alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Snca, Syn, a-Synuclein, ATGP0619-10ug, ATGP0619-20ug, ATGP0619-50ug, ATGP0619-100ug, ATGP0619-250ug, ATGP0619-500ug, ATGP0619-1mg, ATGP0619-10, ATGP0619-20, ATGP0619-50, ATGP0619-100, ATGP0619-250, ATGP0619-500, ATGP0619-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
14.4 kDa (140aa) confirmed by MALDI-TOF
Description
Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 10% glycerol
Antigen Species
Mouse
Gene Category
Neuroscience
Domain
1-140aa
Species of Protein
Mouse
Manufacturer - Search Terms
a-Synuclein, alpha-Synuclein, Snca, Syn, alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, ATGP0619-10ug, ATGP0619-20ug, ATGP0619-50ug, ATGP0619-100ug, ATGP0619-250ug, ATGP0619-500ug, ATGP0619-1mg, ATGP0619-10, ATGP0619-20, ATGP0619-50, ATGP0619-100, ATGP0619-250, ATGP0619-500, ATGP0619-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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