Recombinant human TSTA3 protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

TSTA3 is a NADP (H) -binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. Recombinant human TSTA3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl

Metabolism

< 1 EU per 1ug of protein (determined by LAL method)

TSTA3, GDP-L-fucose synthase, FX, P35B, SDR4E1, GDP-L-fucose synthase, ATGP0657-10ug, ATGP0657-20ug, ATGP0657-50ug, ATGP0657-100ug, ATGP0657-250ug, ATGP0657-500ug, ATGP0657-1mg, ATGP0657-10, ATGP0657-20, ATGP0657-50, ATGP0657-100, ATGP0657-250, ATGP0657-500, ATGP0657-1