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Recombinant human PD-ECGF/TYMP protein

ArtNr NKM-ATGP0732-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MAPPAPGDFS GEGSQGLPDP SPEPKQLPEL IRMKRDGGRL SEADIRGFVA AVVNGSAQGA QIGAMLMAIR LRGMDLEETS VLTQALAQSG QQLEWPEAWR QQLVDKHSTG GVGDKVSLVL APALAACGCK VPMISGRGLG HTGGTLDKLE SIPGFNVIQS PEQMQVLLDQ AGCCIVGQSE QLVPADGILY AARDVTATVD SLPLITASIL SK
Citations Heldin C H., et al. (1991) J Cell Biochem. 47:208-210.
Furukawa T., et al. (1992) Nature. 356:668.

Matsumae G, et al. Targeting thymidine phosphorylase as a potential therapy for bone loss associated with periprosthetic osteolysis. (BioengTransl Med. 2021){https://pubmed.ncbi.nlm.nih.gov/34589604/}
NCBI NP_001107228
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Thymidine phosphorylase,ECGF1,hPD-ECGF,MNGIE,PDECGF,TP,Gliostatin,Platelet-derived endothelial cell growth factor,TdRPase
Similar products TYMP, TP, ECGF1, MNGIE, PDECGF, hPD-ECGF, PD-ECGF, Thymidine Phosphorylase, Gliostatin, Thymidine phosphorylase, ATGP0732-10ug, ATGP0732-20ug, ATGP0732-50ug, ATGP0732-100ug, ATGP0732-250ug, ATGP0732-500ug, ATGP0732-1mg, ATGP0732-10, ATGP0732-20, ATGP0732-50, ATGP0732-100, ATGP0732-250, ATGP0732-500, ATGP0732-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
51.3 kDa (493aa) confirmed by MALDI-TOF
Description
Thymidine phosphorylase precursor, also known TYMP, is a platelet-derived endothelial cell growth factor that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. It is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Increased expression of TYMP is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis. Recombinant human TYMP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Growth factors
Domain
11-482aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
PD-ECGF, Thymidine Phosphorylase, TYMP, Thymidine phosphorylase, ECGF1, hPD-ECGF, MNGIE, PDECGF, TP, Gliostatin, Thymidine phosphorylase, ATGP0732-10ug, ATGP0732-20ug, ATGP0732-50ug, ATGP0732-100ug, ATGP0732-250ug, ATGP0732-500ug, ATGP0732-1mg, ATGP0732-10, ATGP0732-20, ATGP0732-50, ATGP0732-100, ATGP0732-250, ATGP0732-500, ATGP0732-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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