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Recombinant human MafG protein

ArtNr NKM-ATGP1268-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MTTPNKGNKA LKVKREPGEN GTSLTDEELV TMSVRELNQH LRGLSKEEIV QLKQRRRTLK NRGYAASCRV KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART VARSPVAPAR GPLAAGLGPL VPGKVAATSV ITIVKSKTDA RS
Citations Hung H.-L., et al. (2001) J. Biol. Chem. 276:10715-10721
Blank V., et al. (1997) Genomics. 44:147-149
Lacher SE, et al. Beyond antioxidant genes in the ancient NRF2 regulatory network. (Free Radic Biol Med. 2015){https://pubmed.ncbi.nlm.nih.gov/26163000/}
Lacher SE, et al. A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimers disease. (Redox Biol. 2018){https://pubmed.ncbi.nlm.nih.gov/29179108/}
Lacher SE, et al. An antioxidant response element regulates the HIF1α axis in breast cancer cells. (Free Radic Biol Med. 2023){https://pubmed.ncbi.nlm.nih.gov/37179033/}
NCBI NP_116100.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Transcription factor MafG,hMAF,MAFG,V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
Similar products Transcription factor MafG, hMAF, MafG, ATGP1268-10ug, ATGP1268-20ug, ATGP1268-50ug, ATGP1268-100ug, ATGP1268-250ug, ATGP1268-500ug, ATGP1268-1mg, ATGP1268-10, ATGP1268-20, ATGP1268-50, ATGP1268-100, ATGP1268-250, ATGP1268-500, ATGP1268-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20 kDa (182aa) confirmed by MALDI-TOF
Description
MAFG, also known as transcription factor MafG, belongs to the Maf family. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Recombinant human MAFG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-162aa
Species of Protein
Human
Manufacturer - Search Terms
MafG, Transcription factor MafG, hMAF, ATGP1268-10ug, ATGP1268-20ug, ATGP1268-50ug, ATGP1268-100ug, ATGP1268-250ug, ATGP1268-500ug, ATGP1268-1mg, ATGP1268-10, ATGP1268-20, ATGP1268-50, ATGP1268-100, ATGP1268-250, ATGP1268-500, ATGP1268-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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