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Recombinant human RAB23 protein

ArtNr NKM-ATGP1290-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GG
Citations Marcos I. et al. (2003) Int J Mol Med. 12:983-987.
Eggenschwiler JT. et al. (2001) Nature. 412:194-198.
NCBI NP_057361
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Ras-related protein Rab-23,DKFZp781H0695,HSPC137,MGC8900,RAB23 member RAS oncogene family
Similar products RAB23, Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900, ATGP1290-10ug, ATGP1290-20ug, ATGP1290-50ug, ATGP1290-100ug, ATGP1290-250ug, ATGP1290-500ug, ATGP1290-1mg, ATGP1290-10, ATGP1290-20, ATGP1290-50, ATGP1290-100, ATGP1290-250, ATGP1290-500, ATGP1290-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28.5 kDa (254aa) confirmed by MALDI-TOF
Description
RAB23, also known as ras-related protein Rab23, is a member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. This protein is thought to to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 may result in Carpenter syndrome a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis. Recombinant human RAB23 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 1mM DTT, 0.1mM PMSF
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-234aa
Species of Protein
Human
Manufacturer - Search Terms
RAB23, Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900, ATGP1290-10ug, ATGP1290-20ug, ATGP1290-50ug, ATGP1290-100ug, ATGP1290-250ug, ATGP1290-500ug, ATGP1290-1mg, ATGP1290-10, ATGP1290-20, ATGP1290-50, ATGP1290-100, ATGP1290-250, ATGP1290-500, ATGP1290-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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