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Recombinant human CCND2 protein

ArtNr NKM-ATGP1342-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMELLCH EVDPVRRAVR DRNLLRDDRV LQNLLTIEER YLPQCSYFKC VQKDIQPYMR RMVATWMLEV CEEQKCEEEV FPLAMNYLDR FLAGVPTPKS HLQLLGAVCM FLASKLKETS PLTAEKLCIY TDNSIKPQEL LEWELVVLGK LKWNLAAVTP HDFIEHILRK LPQQREKLSL IRKHAQTFIA LCATDFKFAM YPPSMIATGS VG
Citations Inaba T., et al. (1992) Genomics. 13(3):565-74.
Wang Z., et al. (2008) Cell Struct Funct. 33(2):171-83.
NCBI NP_001750
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cyclin D2,KIAK0002,MGC102758,G1/S-specific cyclin-D2
Similar products Cyclin D2, CCND2, G1/S-specific cyclin-D2, KIAK0002, MGC102758, ATGP1342-10ug, ATGP1342-20ug, ATGP1342-50ug, ATGP1342-100ug, ATGP1342-250ug, ATGP1342-500ug, ATGP1342-1mg, ATGP1342-10, ATGP1342-20, ATGP1342-50, ATGP1342-100, ATGP1342-250, ATGP1342-500, ATGP1342-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
35.6 kDa (313aa)
Description
CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of this protein was observed in ovarian and testicular tumors. Recombinant human CCND2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 1M urea.
Antigen Species
Human
Gene Category
Cancer
Domain
1-289aa
Species of Protein
Human
Manufacturer - Search Terms
CCND2, Cyclin D2, KIAK0002, MGC102758, G1/S-specific cyclin-D2, ATGP1342-10ug, ATGP1342-20ug, ATGP1342-50ug, ATGP1342-100ug, ATGP1342-250ug, ATGP1342-500ug, ATGP1342-1mg, ATGP1342-10, ATGP1342-20, ATGP1342-50, ATGP1342-100, ATGP1342-250, ATGP1342-500, ATGP1342-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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