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Recombinant human TARS1 protein

ArtNr NKM-ATGP1417-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MFEEKASSPS GKMGGEEKPI GAGEEKQKEG GKKKNKEGSG DGGRAELNPW PEYIYTRLEM YNILKAEHDS ILAEKAEKDS KPIKVTLPDG KQVDAESWKT TPYQIACGIS QGLADNTVIA KVNNVVWDLD RPLEEDCTLE LLKFEDEEAQ AVYWHSSAHI MGEAMERVYG GCLCYGPPIE NGFYYDMYLE EGGVSSNDFS SLEALCKKII
Citations Freist W, et al. (1995). Biol. Chem. Hoppe-Seyler 376 (4): 213-24.
Pan F, et al. (1982). Int. J. Pept. Protein Res. 20 (2): 159-66.
Wang W, et al. The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. (Nat Med. 2016){https://pubmed.ncbi.nlm.nih.gov/27348499/}
NCBI NP_689508
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias threonyl-tRNA synthetase cytoplasmic,threonyl-tRNA synthetase,cytoplasmic,ThrRS
Similar products TDP43, TARDBP, cytoplasmic, ThrRS, threonyl-tRNA synthetase, threonyl-tRNA synthetase cytoplasmic, ATGP1417-10ug, ATGP1417-20ug, ATGP1417-50ug, ATGP1417-100ug, ATGP1417-250ug, ATGP1417-500ug, ATGP1417-1mg, ATGP1417-10, ATGP1417-20, ATGP1417-50, ATGP1417-100, ATGP1417-250, ATGP1417-500, ATGP1417-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
85.6 kDa (743aa)
Description
TARS (Threonyl-tRNA synthetase, cytoplasmic) belongs to the class-II aminoacyl-tRNA synthetase family. This protein has its main role in tRNA aminoacylation. The N-terminal domain of the enzyme is responsible for the competition with the ribosome whilst the catalytic and the C-terminal domain are involved in binding the two anticodon arm-like structures in the operator. Recombinant human TARS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
Antigen Species
Human
Gene Category
Metabolism
Domain
1-723aa
Species of Protein
Human
Manufacturer - Search Terms
TDP43, TARDBP, threonyl-tRNA synthetase cytoplasmic, threonyl-tRNA synthetase, cytoplasmic, ThrRS, ATGP1417-10ug, ATGP1417-20ug, ATGP1417-50ug, ATGP1417-100ug, ATGP1417-250ug, ATGP1417-500ug, ATGP1417-1mg, ATGP1417-10, ATGP1417-20, ATGP1417-50, ATGP1417-100, ATGP1417-250, ATGP1417-500, ATGP1417-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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