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Recombinant human Casein kinase 2 alpha 1/CSNK2A1 protein

ArtNr NKM-ATGP1455-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMMSGPV PSRARVYTDV NTHRPREYWD YESHVVEWGN QDDYQLVRKL GRGKYSEVFE AINITNNEKV VVKILKPVKK KKIKREIKIL ENLRGGPNII TLADIVKDPV SRTPALVFEH VNNTDFKQLY QTLTDYDIRF YMYEILKALD YCHSMGIMHR DVKPHNVMID HEHRKLRLID WGLAEFYHPG QEYNVRVASR YFKGPELLVD YQ
Citations Prudent R., et al. (2010) Cancer Res. 70:9865-9874
Deloukas P., et al. (2001) Nature. 414:865-871

Yoo JY, et al. Nuclear hormone receptor corepressor promotes esophageal cancer cell invasion by transcriptional repression of interferon-γ-inducible protein 10 in a casein kinase 2-dependent manner. (Mol Biol Cell. 2012){https://pubmed.ncbi.nlm.nih.gov/22675025/}
Yoo JY, et al. CK2-NCoR signaling cascade promotes prostate tumorigenesis. (Oncotarget. 2013){https://pubmed.ncbi.nlm.nih.gov/23669876/}
Stakkestad Ø, et al. Phosphorylation Modulates Ameloblastin Self-assembly and Ca 2+ Binding. (Front Physiol. 2017){https://pubmed.ncbi.nlm.nih.gov/28798693/}
Ko H, et al. Phosphorylation-dependent stabilization of MZF1 upregulates N-cadherin expression during protein kinase CK2-mediated epithelial-mesenchymal transition. (Oncogenesis. 2018){https://pubmed.ncbi.nlm.nih.gov/29540671/}
NCBI NP_001886
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Casein kinase 2 alpha 1,Casein kinase II subunit alpha,CK II alpha,CK2A1,Cka1,Cka2
Similar products CK2A1, Casein kinase II subunit alpha, CKII, Casein Kinase2 a, ATGP1455-10ug, ATGP1455-20ug, ATGP1455-50ug, ATGP1455-100ug, ATGP1455-250ug, ATGP1455-500ug, ATGP1455-1mg, ATGP1455-10, ATGP1455-20, ATGP1455-50, ATGP1455-100, ATGP1455-250, ATGP1455-500, ATGP1455-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
47.8 kDa (416aa) confirmed by MALDI-TOF
Description
CSNK2A1, also known as casein kinase II subunit alpha, are catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. It regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. CSNK2A1 may act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. Recombinant human CSNK2A1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
Antigen Species
Human
Gene Category
Cell Cycle
Domain
1-391aa
Species of Protein
Human
Manufacturer - Search Terms
Casein Kinase2 a, Casein kinase II subunit alpha, CK2A1, CKII, ATGP1455-10ug, ATGP1455-20ug, ATGP1455-50ug, ATGP1455-100ug, ATGP1455-250ug, ATGP1455-500ug, ATGP1455-1mg, ATGP1455-10, ATGP1455-20, ATGP1455-50, ATGP1455-100, ATGP1455-250, ATGP1455-500, ATGP1455-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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