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Recombinant human Bcl-10 protein

ArtNr NKM-ATGP1457-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSH>MEPTAP SLTEEDLTEV KKDALENLRV YLCEKIIAER HFDHLRAKKI LSREDTEEIS CRTSSRKRAG KLLDYLQENP KGLDTLVESI RREKTQNFLI QKITDEVLKL RNIKLEHLKG LKCSSCEPFP DGATNNLSRS NSDESNFSEK LRASTVMYHP EGESSTTPFF STNSSLNLPV LEVGRTENTI FSSTTLPRPG DPGAPPLPPD
Citations Rebeaud F., et al. (2008) Nat. Immunol. 9:272-281
Yui D., et al. (2001) Oncogene. 20:4317-4323
NCBI NP_003912
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias B cell CLL/lymphoma 10,BCL10,Immune signaling adaptor,CARMEN,CIPER,mE10,c-E10,CLAP
Similar products BCL10, CARMEN, CIPER, CLAP, c-E10, mE10, B cell CLL/lymphoma 10, c E10, B-cell lymphoma/leukemia 10, IMD37, Immune signaling adaptor, B cell lymphoma/leukemia 10, Ce10, ATGP1457-10ug, ATGP1457-20ug, ATGP1457-50ug, ATGP1457-100ug, ATGP1457-250ug, ATGP1457-500ug, ATGP1457-1mg, ATGP1457-010, ATGP1457-020, ATGP1457-050, ATGP1457-100, ATGP1457-250, ATGP1457-500, ATGP1457-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28.8 kDa (257aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
BCL10, also known as B-cell lymphoma/leukemia 10, contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. It is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Recombinant human BCL10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-233aa
Species of Protein
Human
Manufacturer - Search Terms
, B cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, CARMEN, c-E10, CIPER, CLAP, IMD37, Immune signaling adaptor, mE10, B cell lymphoma/leukemia 10, c E10, Ce10, ATGP1457-10ug, ATGP1457-20ug, ATGP1457-50ug, ATGP1457-100ug, ATGP1457-250ug, ATGP1457-500ug, ATGP1457-1mg, ATGP1457-010, ATGP1457-020, ATGP1457-050, ATGP1457-100, ATGP1457-250, ATGP1457-500, ATGP1457-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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