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Recombinant human IL-12 p40 protein

ArtNr NKM-ATGP1483-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>IWELKKD VYVVELDWYP DAPGEMVVLT CDTPEEDGIT WTLDQSSEVL GSGKTLTIQV KEFGDAGQYT CHKGGEVLSH SLLLLHKKED GIWSTDILKD QKEPKNKTFL RCEAKNYSGR FTCWWLTTIS TDLTFSVKSS RGSSDPQGVT CGAATLSAER VRGDNKEYEY SVECQEDSAC PAAEESLPIE VMVDAVHKLK YENYTSSFFI RDIIKPDPPK NLQLKPLKNS
Citations Oppmann B., et al (2000) Immunity 13:715-725(2000)
Presky et al. (1996) Proc. Natl. Acad. Sci. u.S.A. 93 (24): 14002-7.
NCBI NP_002178
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin 12B,Interleukin-12 beta chain,IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,interleukin 12 p40,NK cell stimulatory factor chain 2,NKSF2,CLMF2
Similar products IL12B, IL-12B, NKSF2, CLMF, CLMF2, NKSF, IL12 p40, interleukin 12 subuit beta, ATGP1483-10ug, ATGP1483-20ug, ATGP1483-50ug, ATGP1483-100ug, ATGP1483-250ug, ATGP1483-500ug, ATGP1483-1mg, ATGP1483-10, ATGP1483-20, ATGP1483-50, ATGP1483-100, ATGP1483-250, ATGP1483-500, ATGP1483-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
35.8 kDa (315aa)
Description
IL12P40 (interleukin 12 subunit beta), also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40, belongs to the type I cytokine receptor family. This protein is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. Recombinant human IL12P40 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl, 0.1mM PMSF
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
23-328aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
IL12B, IL12 p40, interleukin 12 subuit beta, CLMF, NKSF, CLMF2, NKSF2, IL-12B, ATGP1483-10ug, ATGP1483-20ug, ATGP1483-50ug, ATGP1483-100ug, ATGP1483-250ug, ATGP1483-500ug, ATGP1483-1mg, ATGP1483-10, ATGP1483-20, ATGP1483-50, ATGP1483-100, ATGP1483-250, ATGP1483-500, ATGP1483-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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