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Recombinant human p21/CIP1/CDKN1A protein

ArtNr NKM-ATGP1725-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 4 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSEPAGDVRQ NPCGSKACRR LFGPVDSEQL SRDCDALMAG CIQEARERWN FDFVTETPLE GDFAWERVRG LGLPKLYLPT GPRRGRDELG GGRRPGTSPA LLQGTAEEDH VDLSLSCTLV PRSGEQAEGS PGGPGDSQGR KRRQTSMTDF YHSKRRLIFS KRKP
Citations EI-Deiry W S., et al. (1994) Cancer Res. 54:1169-1174.
Harper J W., et al. (1993) Cell. 75:805-816.
NCBI NP_000380.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cyclin-dependent kinase inhibitor 1A,P21,CIP1,SDI1,WAF1,CAP20,CDKN1,MDA-6,p21CIP1
Similar products p21, CDKN1A, CAP20, CDKN1, CIP1, SDI1, WAF1, MDA-6, P21, p21CIP1, Cyclin-dependent kinase inhibitor 1A, ATGP1725-10ug, ATGP1725-20ug, ATGP1725-50ug, ATGP1725-100ug, ATGP1725-250ug, ATGP1725-500ug, ATGP1725-1mg, ATGP1725-10, ATGP1725-20, ATGP1725-50, ATGP1725-100, ATGP1725-250, ATGP1725-500, ATGP1725-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20.2 kDa (184aa)
Description
CDKN1A, also known as P21 or WAF1, plays a critical role in the cellular response to DNA damage, and its overexpression results in cell cycle arrest. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, CDKN1A may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D. This protein may be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Recombinant human CDKN1A protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Cancer
Domain
1-164aa
Species of Protein
Human
Manufacturer - Search Terms
p21, CIP1, CDKN1A, Cyclin-dependent kinase inhibitor 1A, P21, CIP1, SDI1, WAF1, CAP20, CDKN1, MDA-6, p21CIP1, ATGP1725-10ug, ATGP1725-20ug, ATGP1725-50ug, ATGP1725-100ug, ATGP1725-250ug, ATGP1725-500ug, ATGP1725-1mg, ATGP1725-10, ATGP1725-20, ATGP1725-50, ATGP1725-100, ATGP1725-250, ATGP1725-500, ATGP1725-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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