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Recombinant human UMPS protein

ArtNr NKM-ATGP1788-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MAVARAALGP LVTGLYDVQA FKFGDFVLKS GLSSPIYIDL RGIVSRPRLL SQVADILFQT AQNAGISFDT VCGVPYTALP LATVICSTNQ IPMLIRRKET KDYGTKRLVE GTINPGETCL IIEDVVTSGS SVLETVEVLQ KEGLKVTDAI VLLDREQGGK DKLQAHGIRL HSVCTLSKML EILEQQKKVD AETVGRVKRF IQENVFVAAN HN
Citations Suchi M., et al. (1997) Genet. 60:525-539.
Yablonski M J., et al. (1996) J Biol Chem. 271:10704-10708.
NCBI NP_000364
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias uridine 5'-monophosphate synthase,OPRT
Similar products UMPS, OPRT, uridine 5'-monophosphate synthase, ATGP1788-10ug, ATGP1788-20ug, ATGP1788-50ug, ATGP1788-100ug, ATGP1788-250ug, ATGP1788-500ug, ATGP1788-1mg, ATGP1788-10, ATGP1788-20, ATGP1788-50, ATGP1788-100, ATGP1788-250, ATGP1788-500, ATGP1788-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.3 kDa (500aa)
Description
uridine 5'-monophosphate synthase, also known as uMPS, is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. unlike prokaryotes, uMPS in eukaryotes combines the orotate phosphoribosyltransferase and the orotidine-5'-monophosphate (OMP) decarboxylase activities into a single protein. The union of these two enzymes is thought to stabilize the catalytic centers due to the low molar concentration of the protein in mammalian cells. Defects in this gene are the cause of hereditary orotic aciduria. Recombinant human uMPS protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Antigen Species
Human
Gene Category
Metabolism
Domain
1-480aa
Species of Protein
Human
Manufacturer - Search Terms
UMPS, uridine 5'-monophosphate synthase, OPRT, ATGP1788-10ug, ATGP1788-20ug, ATGP1788-50ug, ATGP1788-100ug, ATGP1788-250ug, ATGP1788-500ug, ATGP1788-1mg, ATGP1788-10, ATGP1788-20, ATGP1788-50, ATGP1788-100, ATGP1788-250, ATGP1788-500, ATGP1788-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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