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Recombinant human Beclin 1/BECN1 protein

ArtNr NKM-ATGP1816-4ug
Hersteller NKMAX
Menge 4 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MEGSKTSNNS TMQVSFVCQR CSQPLKLDTS FKILDRVTIQ ELTAPLLTTA QAKPGETQEE ETNSGEEPFI ETPRQDGVSR RFIPPARMMS TESANSFTLI GEASDGGTME NLSRRLKVTG DLFDIMSGQT DVDHPLCEEC TDTLLDQLDT QLNVTENECQ NYKRCLEILE QMNEDDSEQL QMELKELALE EERLIQELED VEKNRKIVAE
Citations Sagona A.P., et al. (2010) Nat. Cell Biol. 12:362-371
Itakura E., et al. (2008) Mol. Biol. Cell 19:5360-5372
NCBI NP_003757.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Beclin 1,Coiled-coil myosin-like BCL2-interacting protein,Protein GT197,Beclin 1 autophagy related,ATG6,ATG6 autophagy related 6 homolog,VPS30
Similar products ATG6, VPS30, beclin1, beclin 1, Beclin1, ATGP1816-10ug, ATGP1816-20ug, ATGP1816-50ug, ATGP1816-100ug, ATGP1816-250ug, ATGP1816-500ug, ATGP1816-1mg, ATGP1816-10, ATGP1816-20, ATGP1816-50, ATGP1816-100, ATGP1816-250, ATGP1816-500, ATGP1816-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
54.1 kDa (470aa)
Description
BECN1, also as known as Beclin-1 and autophagy-related gene (Atg) 6, belongs to the beclin family. This protein plays a central role in autophagy. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy. Also it required for the abcission step of cytokinesis. BECN1 plays a role in antiviral host defense. Recombinant human BECN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional column chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Metabolism
Domain
1-450aa
Species of Protein
Human
Manufacturer - Search Terms
Beclin1, beclin 1, ATG6, beclin1, VPS30, ATGP1816-10ug, ATGP1816-20ug, ATGP1816-50ug, ATGP1816-100ug, ATGP1816-250ug, ATGP1816-500ug, ATGP1816-1mg, ATGP1816-10, ATGP1816-20, ATGP1816-50, ATGP1816-100, ATGP1816-250, ATGP1816-500, ATGP1816-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 4 ug
Lieferbar: In stock
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