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Recombinant human AMPK beta 2 protein

ArtNr NKM-ATGP1817-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSH>MGNTTS DRVSGERHGA KAARSEGAGG HAPGKEHKIM VGSTDDPSVF SLPDSKLPGD KEFVSWQQDL EDSVKPTQQA RPTVIRWSEG GKEVFISGSF NNWSTKIPLI KSHNDFVAIL DLPEGEHQYK FFVDGQWVHD PSEPVVTSQL GTINNLIHVK KSDFEVFDAL KLDSMESSET SCRDLSSSPP GPYGQEMYAF RSEERFKSPP
Citations Souza RP. et al. (2012) J Psychiatr Res. 46:462-468.
Jung KC. et al. (2003) Cytogenet Genome Res. 103:202C.
NCBI NP_005390
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 5'-AMP-activated protein kinase subunit beta-2
Similar products 5'-AMP-activated protein kinase subunit beta-2, AMPK b2, ATGP1817-10ug, ATGP1817-20ug, ATGP1817-50ug, ATGP1817-100ug, ATGP1817-250ug, ATGP1817-500ug, ATGP1817-1mg, ATGP1817-10, ATGP1817-20, ATGP1817-50, ATGP1817-100, ATGP1817-250, ATGP1817-500, ATGP1817-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
32.8 kDa (296aa)
Description
PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Recombinant human PRKAB2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea
Antigen Species
Human
Gene Category
Metabolism
Domain
1-272aa
Species of Protein
Human
Manufacturer - Search Terms
AMPK b2, 5'-AMP-activated protein kinase subunit beta-2, ATGP1817-10ug, ATGP1817-20ug, ATGP1817-50ug, ATGP1817-100ug, ATGP1817-250ug, ATGP1817-500ug, ATGP1817-1mg, ATGP1817-10, ATGP1817-20, ATGP1817-50, ATGP1817-100, ATGP1817-250, ATGP1817-500, ATGP1817-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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