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Recombinant human Endocan/ESM1 protein

ArtNr NKM-ATGP1864-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>WSNNYAV DCPQHCDSSE CKSSPRCKRT VLDDCGCCRV CAAGRGETCY RTVSGMDGMK CGPGLRCQPS NGEDPFGEEF GICKDCPYGT FGMDCRETCN CQSGICDRGT GKCLKFPFFQ YSVTKSSNRF VSLTEHDMAS GDGNIVREEV VKENAAGSPV MRKWLNPR
Citations Scherpereel A., et al. (2003) Cancer Res. 63:6084.
Bechard D., et al. (2000) J Vasc Res. 37:417.
NCBI NP_008967.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Endocan,Endothelial cell-specific molecule 1,Endothelial cell-specific molecule 1 isoform a,ESM1
Similar products ESM1, Endocan, Endothelial cell-specific molecule 1, Endothelial cell-specific molecule 1 isoform a, ATGP1864-10ug, ATGP1864-20ug, ATGP1864-50ug, ATGP1864-100ug, ATGP1864-250ug, ATGP1864-500ug, ATGP1864-1mg, ATGP1864-010, ATGP1864-020, ATGP1864-050, ATGP1864-100, ATGP1864-250, ATGP1864-500, ATGP1864-01M
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20.5 kDa (188aa)
Description
Endothelial cell-specific molecule 1, also known as ESM1, is a proteoglycan secreted by endothelial cells and its mRNA expression is regulated by inflammatory cytokines. ESM1 expression has also been detected in different epithelia and in adipocytes. The expression of endocan is upregulated by TNF alpha, IL1 beta, or lipopolysaccharide and downregulated by IFN gamma. Genetically engineered cells overexpressing endocan has been shown to induce tumor formation, suggesting that ESM1 may be involved in the pathophysiology of tumor growth in vivo. Recombinant human ESM1 protein, fused to His-tag at N-terminus, was expressed in E. coli
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol
Antigen Species
Human
Gene Category
Angiogenesis
Domain
20-184aa
Species of Protein
Human
Manufacturer - Search Terms
Endocan, Endothelial cell-specific molecule 1, Endothelial cell-specific molecule 1 isoform a, ESM1, ATGP1864-10ug, ATGP1864-20ug, ATGP1864-50ug, ATGP1864-100ug, ATGP1864-250ug, ATGP1864-500ug, ATGP1864-1mg, ATGP1864-010, ATGP1864-020, ATGP1864-050, ATGP1864-100, ATGP1864-250, ATGP1864-500, ATGP1864-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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