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Recombinant human Bub3 protein

ArtNr NKM-ATGP1929-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMTGSNEF KLNQPPEDGI SSVKFSPNTS QFLLVSSWDT SVRLYDVPAN SMRLKYQHTG AVLDCAFYDP THAWSGGLDH QLKMHDLNTD QENLVGTHDA PIRCVEYCPE VNVMVTGSWD QTVKLWDPRT PCNAGTFSQP EKVYTLSVSG DRLIVGTAGR RVLVWDLRNM GYVQQRRESS LKYQTRCIRA FPNKQGYVLS SIEGRVAVEY LD
Citations Martinez Exposito M J., et al. (1999) Proc Natl Acad Sci uSA. 96:8493-8498.
Warren C D., et al. (2002) Mol Biol Cell. 13:3029-3041.
NCBI NP_004716
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mitotic checkpoint protein BuB3,BuB3L,hBuB3
Similar products Bub3, Mitotic checkpoint protein BuB3, BuB3L, hBuB3, ATGP1929-10ug, ATGP1929-20ug, ATGP1929-50ug, ATGP1929-100ug, ATGP1929-250ug, ATGP1929-500ug, ATGP1929-1mg, ATGP1929-10, ATGP1929-20, ATGP1929-50, ATGP1929-100, ATGP1929-250, ATGP1929-500, ATGP1929-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
39.5 kDa (351aa)
Description
Mitotic checkpoint protein BuB3, also known as BuB3, is a conserved component of the mitotic spindle assembly complex (MCC). The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BuB3 protein. BuB3 is essential for the kinetochore localization of BuB1 and BuBR1. BuB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. In addition, BuB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. Recombinant human BuB3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Cell Cycle
Domain
1-328aa
Species of Protein
Human
Manufacturer - Search Terms
Bub3, Mitotic checkpoint protein BuB3, BuB3L, hBuB3, ATGP1929-10ug, ATGP1929-20ug, ATGP1929-50ug, ATGP1929-100ug, ATGP1929-250ug, ATGP1929-500ug, ATGP1929-1mg, ATGP1929-10, ATGP1929-20, ATGP1929-50, ATGP1929-100, ATGP1929-250, ATGP1929-500, ATGP1929-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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