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Recombinant human CTLA4 protein

ArtNr NKM-ATGP1959-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>KAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD
Citations Rudd CE, Taylor A, et al. (2009). Immunol Rev. 229(1):12-26.
Stamper CC, Zhang Y, et al. (2001). Nature. 410(6828):608-11.
NCBI NP_005205.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152,CELIAC3,Celiac disease 3,Insulin-dependent diabetes mellitus 12,IDDM12,CD,GSE
Similar products ICOS, CD152, CTLA4, CD, CELIAC3, GRD4, GSE, IDDM12, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, ATGP1959-10ug, ATGP1959-20ug, ATGP1959-50ug, ATGP1959-100ug, ATGP1959-250ug, ATGP1959-500ug, ATGP1959-1mg, ATGP1959-10, ATGP1959-20, ATGP1959-50, ATGP1959-100, ATGP1959-250, ATGP1959-500, ATGP1959-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
15.9 kDa (149aa)
Description
CTLA4 is a member of the immunoglobulin superfamily and transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Recombinant human CTLA4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
36-161aa
Species of Protein
Human
Manufacturer - Search Terms
CTLA4, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12, ATGP1959-10ug, ATGP1959-20ug, ATGP1959-50ug, ATGP1959-100ug, ATGP1959-250ug, ATGP1959-500ug, ATGP1959-1mg, ATGP1959-10, ATGP1959-20, ATGP1959-50, ATGP1959-100, ATGP1959-250, ATGP1959-500, ATGP1959-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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