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Recombinant human RAP2B protein

ArtNr NKM-ATGP1966-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMREYKVV VLGSGGVGKS ALTVQFVTGS FIEKYDPTIE DFYRKEIEVD SSPSVLEILD TAGTEQFASM RDLYIKNGQG FILVYSLVNQ QSFQDIKPMR DQIIRVKRYE RVPMILVGNK VDLEGEREVS YGEGKALAEE WSCPFMETSA KNKASVDELF AEIVRQMNYA AQPNGDEGCC SACVIL
Citations Culine S., et al. (1989) Int J Cancer. 44:990-994
Beranger F., et al. (1991) Oncogene. 6: 1835-1842.
NCBI NP_002877
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Ras-related protein Rap-2b,RAP2B,Member of RAS oncogene family,Small GTP binding protein,Ras family small GTP binding protein RAP2B
Similar products RAP2B, Ras-related protein Rap-2b, Ras family small GTP binding protein RAP2B, Small GTP binding protein, Ras related protein RAP2B, Ras-related protein RAP2B, Ras related protein Rap 2b, P61225, Member of RAS oncogene family, ATGP1966-10ug, ATGP1966-20ug, ATGP1966-50ug, ATGP1966-100ug, ATGP1966-250ug, ATGP1966-500ug, ATGP1966-1mg, ATGP1966-010, ATGP1966-020, ATGP1966-050, ATGP1966-100, ATGP1966-250, ATGP1966-500, ATGP1966-01M
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.9 kDa (206aa) confirmed by MALDI-TOF
Description
Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-183aa
Species of Protein
Human
Manufacturer - Search Terms
Small GTP binding protein, Ras-related protein Rap-2b, Ras-related protein RAP2B, Ras related protein RAP2B, Ras related protein Rap 2b, Ras family small GTP binding protein RAP2B, RAP2B, P61225, Member of RAS oncogene family, ATGP1966-10ug, ATGP1966-20ug, ATGP1966-50ug, ATGP1966-100ug, ATGP1966-250ug, ATGP1966-500ug, ATGP1966-1mg, ATGP1966-010, ATGP1966-020, ATGP1966-050, ATGP1966-100, ATGP1966-250, ATGP1966-500, ATGP1966-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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