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Recombinant human PIM1 protein

ArtNr NKM-ATGP1997-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH M>YQVGPLLGS GGFGSVYSGI RVSDNLPVAI KHVEKDRISD WGELPNGTRV PMEVVLLKKV SSGFSGVIRL LDWFERPDSF VLILERPEPV QDLFDFITER GALQEELARS FFWQVLEAVR HCHNCGVLHR DIKDENILID LNRGELKLID FGSGALLKDT VYTDFDGTRV YSPPEWIRYH RYHGRSAAVW SLGILLYDMV CGDIPFEHDE
Citations Koike N., et al. (2000) FEBS Lett. 467:17-21
Ionov Y., et al. (2003) Anticancer Res. 23:167-178
NCBI NP_002639.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Non-specific serine/threonine protein kinase,PIM
Similar products PIM1, PIM, Non-specific serine/threonine protein kinase, ATGP1997-10ug, ATGP1997-20ug, ATGP1997-50ug, ATGP1997-100ug, ATGP1997-250ug, ATGP1997-500ug, ATGP1997-1mg, ATGP1997-10, ATGP1997-20, ATGP1997-50, ATGP1997-100, ATGP1997-250, ATGP1997-500, ATGP1997-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
31.4 kDa (274aa) confirmed by MALDI-TOF
Description
PIM1 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This protein is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AuG (CuG) and downstream AuG codons. Recombinant human Pim1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Cancer
Domain
38-290aa
Species of Protein
Human
Manufacturer - Search Terms
PIM1, Non-specific serine/threonine protein kinase, PIM, ATGP1997-10ug, ATGP1997-20ug, ATGP1997-50ug, ATGP1997-100ug, ATGP1997-250ug, ATGP1997-500ug, ATGP1997-1mg, ATGP1997-10, ATGP1997-20, ATGP1997-50, ATGP1997-100, ATGP1997-250, ATGP1997-500, ATGP1997-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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