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Recombinant human SPA17 protein

ArtNr NKM-ATGP2045-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMSIPFSN THYRIPQGFG NLLEGLTREI LREQPDNIPA FAAAYFESLL EKREKTNFDP AEWGSKVEDR FYNNHAFEEQ EPPEKSDPKQ EESQISGKEE ETSVTILDSS EEDKEKEEVA AVKIQAAFRG HIAREEAKKM KTNSLQNEEK EENK
Citations Buchli R., et al. (2002) Biochim. Biophys. Acta. 1578:29-42
Li Z., et al. (2007) Int. J. Cancer. 121:1507-1511
NCBI NP_059121
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Sperm surface protein Sp17,CT22,SP17,SP17-1
Similar products SPA17, SP17, CT22, SP17-1, Sperm surface protein Sp17, ATGP2045-10ug, ATGP2045-20ug, ATGP2045-50ug, ATGP2045-100ug, ATGP2045-250ug, ATGP2045-500ug, ATGP2045-1mg, ATGP2045-10, ATGP2045-20, ATGP2045-50, ATGP2045-100, ATGP2045-250, ATGP2045-500, ATGP2045-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
19.8 kDa (174aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
SPA17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. Recombinant human SPA17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Cancer
Domain
1-151aa
Species of Protein
Human
Manufacturer - Search Terms
SPA17, Sperm surface protein Sp17, CT22, SP17, SP17-1, ATGP2045-10ug, ATGP2045-20ug, ATGP2045-50ug, ATGP2045-100ug, ATGP2045-250ug, ATGP2045-500ug, ATGP2045-1mg, ATGP2045-10, ATGP2045-20, ATGP2045-50, ATGP2045-100, ATGP2045-250, ATGP2045-500, ATGP2045-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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