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Recombinant human GIP protein

ArtNr NKM-ATGP2061-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSEKKEGHF SALPSLPVGS HAKVSSPQPR GPRYAEGTFI SDYSIAMDKI HQQDFVNWLL AQKGKKNDWK HNITQREARA LELAGQANRK EEEAVEPQSS PAKNPSDEDL LRDLLIQELL ACLLDQTNLC RLRSR
Citations O'Harte FP. et al. (1999) Diabetes. 48:758-765
Gault VA. et al. (2002) Biosci Rep. 22:523-528.
NCBI AAH69100
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Gastric inhibitory polypeptide,Glucose-dependent insulinotropic polypeptide,Gastric Inhibitory Peptide
Similar products GIP, Gastric Inhibitory Peptide, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, ATGP2061-10ug, ATGP2061-20ug, ATGP2061-50ug, ATGP2061-100ug, ATGP2061-250ug, ATGP2061-500ug, ATGP2061-1mg, ATGP2061-10, ATGP2061-20, ATGP2061-50, ATGP2061-100, ATGP2061-250, ATGP2061-500, ATGP2061-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
17.3 kDa (155aa) confirmed by MALDI-TOF
Description
GIP, also known as glucose-dependent insulinotropic polypeptide, is an important insulin-releasing hormone of the enteroinsular axis that has a functional profile of possible therapeutic value for type 2 diabetes. This protein is an important incretin hormone released into the circulation from endocrine K-cells of the duodenum and jejunum after ingestion of food1. It was evaluated for their ability to elevate cellular cAMP production and stimulate insulin secretion. It also promotes plasma triglyceride clearance in response to oral fat loading. In liver, GIP has been shown to enhance insulin-dependent inhibition of glycogenolysis. Recombinant human GIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol 0.1M NaCl, 2mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
22-153aa
Species of Protein
Human
Manufacturer - Search Terms
GIP, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Gastric Inhibitory Peptide, ATGP2061-10ug, ATGP2061-20ug, ATGP2061-50ug, ATGP2061-100ug, ATGP2061-250ug, ATGP2061-500ug, ATGP2061-1mg, ATGP2061-10, ATGP2061-20, ATGP2061-50, ATGP2061-100, ATGP2061-250, ATGP2061-500, ATGP2061-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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