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Recombinant human SET protein

ArtNr NKM-ATGP2191-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMAPKRQS PLPPQKKKPR PPPALGPEET SASAGLPKKG EKEQQEAIEH IDEVQNEIDR LNEQASEEIL KVEQKYNKLR QPFFQKRSEL IAKIPNFWVT TFVNHPQVSA LLGEEDEEAL HYLTRVEVTE FEDIKSGYRI DFYFDENPYF ENKVLSKEFH LNESGDPSSK STEIKWKSGK DLTKRSSQTQ NKASRKRQHE EPESFFTWFT DH
Citations Karetsou Z, Emmanouilidou A, et al. (2009). BMC Biochem. 10:10.
Li M, Makkinje A, et al. (1996). J Biol Chem. 271(19):11059-62.
NCBI NP_001116293
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein SET isoform 1,2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA
Similar products SET, PHAPII, 2PP2A, I2PP2A, IGAAD, IPP2A2, TAF-I, TAF-IBETA, Protein SET isoform 1, ATGP2191-10ug, ATGP2191-20ug, ATGP2191-50ug, ATGP2191-100ug, ATGP2191-250ug, ATGP2191-500ug, ATGP2191-1mg, ATGP2191-10, ATGP2191-20, ATGP2191-50, ATGP2191-100, ATGP2191-250, ATGP2191-500, ATGP2191-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
35.9 kDa (313aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
SET inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. Recombinant human SET protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-290aa
Species of Protein
Human
Manufacturer - Search Terms
SET, Protein SET isoform 1, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA, ATGP2191-10ug, ATGP2191-20ug, ATGP2191-50ug, ATGP2191-100ug, ATGP2191-250ug, ATGP2191-500ug, ATGP2191-1mg, ATGP2191-10, ATGP2191-20, ATGP2191-50, ATGP2191-100, ATGP2191-250, ATGP2191-500, ATGP2191-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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