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Recombinant human CD59 protein

ArtNr NKM-ATGP2258-4ug
Hersteller NKMAX
Menge 4 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSLQCYNCP NPTADCKTAV NCSSDFDACL ITKAGLQVYN KCWKFEHCNF NDVTTRLREN ELTYYCCKKD LCNFNEQLEN
Citations Ninomiya H., et al (1992). J. Biol. Chem. 267: 13675-13680
Rudd P.M., et al (1997). J. Biol. Chem. 272:7229-7244
NCBI NP_000602
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD59 glycoprotein,16.3A5,1F5,EJ16,EJ30,EL32,G344,HRF-20,HRF20,MAC-IP,MACIF,MEM43,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18-20
Similar products CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, CD59 glycoprotein, ATGP2258-10ug, ATGP2258-20ug, ATGP2258-50ug, ATGP2258-100ug, ATGP2258-250ug, ATGP2258-500ug, ATGP2258-1mg, ATGP2258-10, ATGP2258-20, ATGP2258-50, ATGP2258-100, ATGP2258-250, ATGP2258-500, ATGP2258-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
11.3 kDa (100aa) confirmed by MALDI-TOF
Description
CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Recombinant human CD59 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Stem Cell
Domain
26-102aa
Species of Protein
Human
Manufacturer - Search Terms
CD59, CD59 glycoprotein, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, ATGP2258-10ug, ATGP2258-20ug, ATGP2258-50ug, ATGP2258-100ug, ATGP2258-250ug, ATGP2258-500ug, ATGP2258-1mg, ATGP2258-10, ATGP2258-20, ATGP2258-50, ATGP2258-100, ATGP2258-250, ATGP2258-500, ATGP2258-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 4 ug
Lieferbar: In stock
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