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Recombinant human PPM1F protein

ArtNr NKM-ATGP2281-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MSSGAPQ KSSPMASGAE ETPGFLDTLL QDFPALLNPE DPLPWKAPGT VLSQEEVEGE LAELAMGFLG SRKAPPPLAA ALAHEAVSQL LQTDLSEFRK LPREEEEEEE DDDEEEKAPV TLLDAQSLAQ SFFNRLWEVA GQWQKQVPLA ARASQRQWLV SIHAIRNTRR KMEDRHVSLP SFNQLFGLSD PVNRAYFAVF DGHGGVDAAR
Citations Tan KM, Chan SL, et al. (2001). J Biol Chem. 276(47):44193-202.
Harvey BP, Banga SS, et al. (2004). J Biol Chem. 279(23):24889-98.
NCBI NP_055449
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein phosphatase 1F,CAMKP,CaMKPase,FEM-2,hFEM-2,POPX2
Similar products PPM1F, POPX2, Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, ATGP2281-10ug, ATGP2281-20ug, ATGP2281-50ug, ATGP2281-100ug, ATGP2281-250ug, ATGP2281-500ug, ATGP2281-1mg, ATGP2281-10, ATGP2281-20, ATGP2281-50, ATGP2281-100, ATGP2281-250, ATGP2281-500, ATGP2281-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
52.2 kDa (477aa)
Description
PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Recombinant human PPM1F protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-454aa
Species of Protein
Human
Manufacturer - Search Terms
PPM1F, Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2, ATGP2281-10ug, ATGP2281-20ug, ATGP2281-50ug, ATGP2281-100ug, ATGP2281-250ug, ATGP2281-500ug, ATGP2281-1mg, ATGP2281-10, ATGP2281-20, ATGP2281-50, ATGP2281-100, ATGP2281-250, ATGP2281-500, ATGP2281-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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