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Recombinant human BEND6 protein

ArtNr NKM-ATGP2441-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSK EELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSS PVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTNEYMA TH
Citations Dai Q. et al. (2013) Development.. 140:1892-1902
Chu J. et al. (2004) J Biol Chem. 279:12337-12345.
NCBI NP_689944
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BEN domain-containing protein 6,bA203B9.1,C6orf65
Similar products BEND6, C6orf65, BEN domain-containing protein 6, bA203B9.1, ATGP2441-10ug, ATGP2441-20ug, ATGP2441-50ug, ATGP2441-100ug, ATGP2441-250ug, ATGP2441-500ug, ATGP2441-1mg, ATGP2441-10, ATGP2441-20, ATGP2441-50, ATGP2441-100, ATGP2441-250, ATGP2441-500, ATGP2441-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
33.6 kDa (302aa) confirmed by MALDI-TOF
Description
BEND6, as known as BEN domain-containing protein 6, is a neural BEN-solo factor that shares many functional attributes with Drosophila Insensitive, a co-repressor for the Drosophila CSL factor. This protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. In addition, its association with Notch- and CBF1-regulated enhancers is promoted by CBF1 and antagonized by activated Notch. In utero electroporation experiments showed that ectopic BEND6 inhibited Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis. Recombinant human BEND6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Antigen Species
Human
Gene Category
Other
Domain
1-279aa
Species of Protein
Human
Manufacturer - Search Terms
BEND6, BEN domain-containing protein 6, bA203B9.1, C6orf65, ATGP2441-10ug, ATGP2441-20ug, ATGP2441-50ug, ATGP2441-100ug, ATGP2441-250ug, ATGP2441-500ug, ATGP2441-1mg, ATGP2441-10, ATGP2441-20, ATGP2441-50, ATGP2441-100, ATGP2441-250, ATGP2441-500, ATGP2441-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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