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Recombinant human PDE6H protein

ArtNr NKM-ATGP2785-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 80% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MSDNTTL PAPASNQGPT TPRKGPPKFK QRQTRQFKSK PPKKGVKGFG DDIPGMEGLG TDITVICPWE AFSHLELHEL AQFGII
Citations Shimizu-Matsumoto A., et al. (1996) Genomics 32:121-124.
NCBI NP_006196
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Retinal cone rhodopsin-sensitive cGMP 3'5'-cyclic phosphodiesterase subunit gamma,Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma,ACHM6,RCD3
Similar products PDE6H, Retinal cone rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma, Retinal cone rhodopsin-sensitive cGMP 3'5'-cyclic phosphodiesterase subunit gamma, ACHM6, RCD3, ATGP2785-10ug, ATGP2785-20ug, ATGP2785-50ug, ATGP2785-100ug, ATGP2785-250ug, ATGP2785-500ug, ATGP2785-1mg, ATGP2785-10, ATGP2785-20, ATGP2785-50, ATGP2785-100, ATGP2785-250, ATGP2785-500, ATGP2785-1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
11.5 kDa (106aa) confirmed by MALDI-TOF
Description
PDE6H is the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A). Recombinant human PDE6H protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-83aa
Species of Protein
Human
Manufacturer - Search Terms
PDE6H, Retinal cone rhodopsin-sensitive cGMP 3'5'-cyclic phosphodiesterase subunit gamma, Retinal cone rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma, ACHM6, RCD3, ATGP2785-10ug, ATGP2785-20ug, ATGP2785-50ug, ATGP2785-100ug, ATGP2785-250ug, ATGP2785-500ug, ATGP2785-1mg, ATGP2785-10, ATGP2785-20, ATGP2785-50, ATGP2785-100, ATGP2785-250, ATGP2785-500, ATGP2785-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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