Recombinant human Carbonic Anhydrase 8/CA8 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, this protein lacks carbonic anhydrase activity (i. e., the reversible hydration of carbon dioxide). It continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3). Recombinant human CA8 protein fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Cancer

Specific activity is > 450pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37C.

Carbonic Anhydrase VIII, Carbonic anhydrase-related protein, CA-VIII, CALS, CAMRQ3, CARP, ATGP3242-10ug, ATGP3242-20ug, ATGP3242-50ug, ATGP3242-100ug, ATGP3242-250ug, ATGP3242-500ug, ATGP3242-1mg, ATGP3242-10, ATGP3242-20, ATGP3242-50, ATGP3242-100, ATGP3242-250, ATGP3242-500, ATGP3242-1