Vergleich

Recombinant human CD27 Ligand/CD70 protein

ArtNr NKM-ATGP3336-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>QRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRP<HH HHHH>
Citations Welten SP., et al. (2013) J. Virol. 87:6851-6865.
Polak ME., et al. (2012) J. Invest. Dermatol. 132:1636-1644.
NCBI NP_001243.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD70 antigen,CD27L,CD27LG,TNFSF7,tumor necrosis factor superfamily member 7
Similar products CD27L, CD27LG, TNFSF7, CD70 antigen, CD27 Ligand, ATGP3336-10ug, ATGP3336-20ug, ATGP3336-50ug, ATGP3336-100ug, ATGP3336-250ug, ATGP3336-500ug, ATGP3336-1mg, ATGP3336-10, ATGP3336-20, ATGP3336-50, ATGP3336-100, ATGP3336-250, ATGP3336-500, ATGP3336-1
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
18.2 kDa (164aa)
Description
CD70, also known as CD70 antigen, is a transmembrane protein in the TNF receptor superfamily. It functions as a co-stimulatory molecule that supports lymphocyte activation and survival. This protein binds to the transmembrane glycoprotein CD27 ligand/CD70 which is expressed on activated B cells, activated T cells, and dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T cell activation, and thus is proliferation of co-stimulated T cells, as well as the generation of cytolytic T cells. Recombinant human CD70, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
39-193aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human CD27/TNFRSF7 (CAT# ATGP3416).
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
CD27 Ligand, TNFSF7, CD70 antigen, CD27L, CD27LG, TNFSF7, ATGP3336-10ug, ATGP3336-20ug, ATGP3336-50ug, ATGP3336-100ug, ATGP3336-250ug, ATGP3336-500ug, ATGP3336-1mg, ATGP3336-10, ATGP3336-20, ATGP3336-50, ATGP3336-100, ATGP3336-250, ATGP3336-500, ATGP3336-1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen